Search
giant bullous emphysema; Vanishing lung syndrome
Epidemiology:
- most commonly occurs in young men with short history of smoking
Pathology:
- upper-lobe predominant emphysema
- air spaces in the lung with < 1 mm wall occupying > 1/3 of hemithorax
Radiology:
- chest X-ray & chest CT
- paraseptal, asymmetric, upper-lobe prodominant giant bullae
Differential diagnosis:
- alpha-1 antitrypsin deficiency
- lower lobe bullous emphysema
- intravenous or inhaled drug abuse
- congenital lung disorders
- congenital cystic adenomatoid malformation
- lower lobe bullous emphysema
General
bullous lung disease
pulmonary emphysema
References
- Davies P, Bradley C.
Vanishing lung syndrome: giant bullous emphysema.
Lancet. 2017 Dec 9;390(10112):2583.
PMID: 28965716
- Sharma N, Justaniah AM, Kanne JP, Gurney JW, Mohammed TL.
PMID: 19704328
J Thorac Imaging. 2009 Aug;24(3):227-30.
PMID: 19704328 Review.