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Germ cell-less protein-like 1-like (GMCL1L, GCL, GMCL1P1)
Function:
- role in spermatogenesis (putative)
- enhances degradation of MDM2 & increases the amount of p53 probably by modulating the nucleocytoplasmic transport
- interacts with TMPO-Beta, TSG101 & TFDP2
- interacts with EMD
Structure: Contains 1 BTB domain (POZ domain)
Compartment: nuclear matrix
General
nuclear protein
phosphoprotein
Properties
SIZE: MW = 60 kD
entity length = 526 aa
COMPARTMENT: cell nucleus
MOTIF: nuclear translocation signal {49-55}
nuclear translocation signal {85-91}
BTB domain {108-178}
MOTIF: Zinc finger
NAME: Zinc finger
EFFECTOR-BOUND: Zn+2
Tyr phosphorylation site {Y424}
Database Correlations
UniProt Q8NEA9
Pfam PF00651
References
UniProt :accession Q8NEA9