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genome editing
Indications:
1) basic medical research
2) clinical applications in somatic cells with effects limited to treated individuals
3) clinical applications in germline cells
Methods:
- RNA-guided CRISPR-Cas9 genome editing system is more efficient, less costly, & easier to use than earlier protein-guided technologies such as zinc finger nucleases & TALENs. [1]
Related
RNA editing
Specific
gene editing
General
procedure
References
- Hynes RO, Coller BS, Porteus M
Toward Responsible Human Genome Editing.
JAMA. Published online April 10, 2017.
PMID: 28395003
http://jamanetwork.com/journals/jama/fullarticle/2618432