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gene with TATA box
Most mammalian genes contain either a TATA-box at 25-30 BP upstream of the transcriptional start site or a GC-rich element at -100 to -200 (as in housekeeping genes).
Interactions
molecular events
Specific
apolipoprotein-E gene
CaM kinase 2-alpha gene
creatine kinase B gene
CYP2A
CYP2E
hematopoietic stem cell leukemia [SCL] gene, tal1 or TCL5
heme oxygenase 1 gene
HIC2 (hypermethylated in cancer 2) gene (HIC1-related gene on chromosome 22)
HMG CoA synthase gene
Ig kappa chain gene
Ig lambda chain gene
IL2 receptor-alpha gene
immunoglobulin heavy chain gene
low-density lipoprotein [LDL] receptor gene
osteocalcin gene
PAC-1 gene
parathyroid hormone [PTH] gene
phosphoenolpyruvate carboxykinase [PEPCK] gene
primary-response gene or immediate-early gene
prodynorphin gene or proenkephalin B gene
proenkephalin gene or proenkephalin A gene
somatostatin gene
U6 snRNA gene
vasoactive intestinal polypeptide [VIP] gene
General
gene
Properties
MOTIF: TATA box
NAME: TATA box
SITE: -30
transcriptional start site
exon
intron
transcriptional termination site
References
Molecular Cell Biology (2nd ed) Darnell J; Lodish H
& Baltimore D (eds), Scientific American Books,
WH Freeman, NY 1990, pg 292