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gene with TATA box

Most mammalian genes contain either a TATA-box at 25-30 BP upstream of the transcriptional start site or a GC-rich element at -100 to -200 (as in housekeeping genes).

Interactions

molecular events

Specific

apolipoprotein-E gene CaM kinase 2-alpha gene creatine kinase B gene CYP2A CYP2E hematopoietic stem cell leukemia [SCL] gene, tal1 or TCL5 heme oxygenase 1 gene HIC2 (hypermethylated in cancer 2) gene (HIC1-related gene on chromosome 22) HMG CoA synthase gene Ig kappa chain gene Ig lambda chain gene IL2 receptor-alpha gene immunoglobulin heavy chain gene low-density lipoprotein [LDL] receptor gene osteocalcin gene PAC-1 gene parathyroid hormone [PTH] gene phosphoenolpyruvate carboxykinase [PEPCK] gene primary-response gene or immediate-early gene prodynorphin gene or proenkephalin B gene proenkephalin gene or proenkephalin A gene somatostatin gene U6 snRNA gene vasoactive intestinal polypeptide [VIP] gene

General

gene

Properties

MOTIF: TATA box NAME: TATA box SITE: -30 transcriptional start site exon intron transcriptional termination site

References

Molecular Cell Biology (2nd ed) Darnell J; Lodish H & Baltimore D (eds), Scientific American Books, WH Freeman, NY 1990, pg 292