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GDP dissociation inhibitor (GDI)
Function:
- inhibits dissociation of GDP from GNRP (guanine nucleotide regulatory protein)
Interactions
molecular events
Specific
drosophila quartet protein
rab GDP dissociation inhibitor, smg p25A GDP dissociation inhibitor or rab3A GDP dissociation inhibitor (rab3A-GDI)
retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; GMP-PDE delta; protein p17 (PDE6D, PDED)
rho/rac GDP dissociation inhibitor
General
enzyme inhibitor
other protein
Properties
COMPARTMENT: cytoplasm
MOTIF: binding site
FOR-BINDING-OF: ras superfamily protein
References
- Bourne HR et al,
The GTPase superfamily: a conserved switch for diverse cell
functions
Nature 348:125 1990
PMID: 2122258
- Matsui Y et al
Molecular cloning and characterization of a novel type of
regulatory protein (GDI) for smg p25A, a ras p21-like GTP-
binding protein.
Mol Cell Biol 1990 Aug;10(8):4116-22
PMID: 2115118
Component-of
molecular complex