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gastroschisis

Etiology: - congenital anomaly associated with young maternal age - association with self-reported prescription opioid use in the first trimester [4] Epidemiology: - prevalence has increased from 3.6 to 4.9 per 10,000 live births in black, white, & Hispanic mothers in all age groups from 1995-2005 to 2006-2012 [3] Pathology: - congenital abdominal wall hernia - infant's intestines stick out of the body through a defect on one side of the umbilical cord Differential diagnosis: - omphalocele: infant's intestines protrude from the umbilicus & are covered with a membrane

General

congenital anomaly (birth defect) abdominal wall hernia (ventral hernia)

References

  1. PubMed Health: Gastroschisis http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001987/
  2. Glasses JG eMedicine (Medscape): Pediatric Omphalocele and Gastroschisis http://emedicine.medscape.com/article/975583-overview
  3. Jones AM et al Increasing Prevalence of Gastroschisis - 14 States, 1995-2012 MMWR Weekly / January 22, 2016 / 65(2);23-26 http://www.cdc.gov/mmwr/volumes/65/wr/mm6502a2.htm
  4. Short TD, Stallings EB, Isenburg J, et al. Gastroschisis Trends and Ecologic Link to Opioid Prescription Rates - United States, 2006-2015. MMWR Morb Mortal Wkly Rep 2019;68:31-36 https://www.cdc.gov/mmwr/volumes/68/wr/mm6802a2.htm