gamma-glutamyltransferase 6 (gamma-glutamyltranspeptidase 6, GGT 6, [contains: gamma-glutamyltransferase 6 heavy chain; gamma-glutamyltransferase 6 light chain], GGT6)

Function: - cleaves glutathione conjugates (putative) - active site is located in the light chain (putative) - glutathione metabolism (5-L-glutamyl)-peptide + an amino acid peptide + 5-L-glutamyl amino acid Structure: - heterodimer composed of the light & heavy chains - belongs to the gamma-glutamyltransferase family Compartment: membrane Alternative splicing: named isoforms=2

General

gamma-glutamyltransferase (GGT) or gamma-glutamyltranspeptidase glycoprotein membrane protein

Properties

SIZE: entity length = 493 aa MW = 51 kD COMPARTMENT: cellular membrane MOTIF: glutamate-rich region {21-30} MOTIF: glutamate residue (SEVERAL) transmembrane domain {55-75} N-glycosylation site {N161} N-glycosylation site {N370}

Database Correlations

UniProt Q6P531 Pfam PF01019 Kegg hsa:1249 ENZYME 2.3.2.2

References

UniProt :accession Q6P531