galanin receptor type 1; GAL1-R; GALR1 (GALR1, GALNR, GALNR1)

Function: - receptor for the hormone galanin - activity is mediated by Gi proteins Structure: - palmitoylated on at least one of the 3 Cys present in the C-terminal part - belongs to the G-protein coupled receptor 1 family Compartment: cell membrane

General

galanin receptor glycoprotein

Properties

SIZE: entity length = 349 aa MW = 39 kD COMPARTMENT: cellular membrane MOTIF: exoplasmic domain {1-36} MOTIF: N-glycosylation site {N7} N-glycosylation site {N12} transmembrane domain {37-57} cytoplasmic loop {58-70} transmembrane domain {71-91} exoplasmic loop {92-109} MOTIF: cysteine residue {C108} MODIFICATION: cysteine residue {C187} transmembrane domain {110-131} cytoplasmic loop {132-151} transmembrane domain {152-172} exoplasmic loop {173-200} MOTIF: N-glycosylation site {N183} cysteine residue {C187} MODIFICATION: cysteine residue {C108} transmembrane domain {201-221} cytoplasmic loop {222-248} transmembrane domain {249-269} exoplasmic loop {270-271} transmembrane domain {272-292} cytoplasmic domain {293-349} MOTIF: cysteine residue {C320} MODIFICATION: palmitate COMPARTMENT: membrane

Database Correlations

OMIM 600377 UniProt P47211 Pfam PF00001 Entrez Gene 2587 Kegg hsa:2587

References

UniProt :accession P47211