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gamma-aminobutyric acid receptor subunit theta; GABA(A) receptor subunit theta (GABRQ)
Function:
- GABA-A receptor subunit
- coassembles with GABRA1, GABRB1, & GABRG1
Structure:
- belongs to the ligand-gated ionic channel (TC 1.A.9) family
Compartment:
- cell junction, synapse, postsynaptic cell membrane
General
glycoprotein
ionotropic receptor subunit
transmembrane 4e protein
Properties
SIZE: entity length = 632 aa
MW = 72 kD
COMPARTMENT: plasma membrane
MOTIF: exoplasmic domain {1-268}
MOTIF: signal sequence {1-21}
N-glycosylation site {N127}
cysteine residue {C183}
MODIFICATION: cysteine residue {C197}
cysteine residue {C197}
MODIFICATION: cysteine residue {C183}
transmembrane domain {269-289}
cytoplasmic loop {290-326}
transmembrane domain {327-347}
exoplasmic loop {348-611}
transmembrane domain {612-632}
exoplasmic domain {632-632}
Database Correlations
OMIM 300349
UniProt Q9UN88
PFAM correlations
Entrez Gene 55879
Kegg hsa:5587
References
UniProt :accession Q9UN88