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gamma-aminobutyric acid receptor subunit gamma-1; GABA(A) receptor subunit gamma-1 (GABRG1)
Function:
- GABA-A receptor gamma subunit
- this subunit carries the benzodiazepine binding site
Structure:
- belongs to the ligand-gated ionic channel (TC 1.A.9) family
Compartment: cell junction, synapse, postsynaptic cell membrane
General
gamma-aminobutyric acid (GABA) A receptor, gamma
glycoprotein
transmembrane 4e protein
Properties
SIZE: entity length = 465 aa
MW = 54 kD
COMPARTMENT: plasma membrane
MOTIF: exoplasmic domain {1-272}
MOTIF: signal sequence {1-35}
N-glycosylation site {N50}
N-glycosylation site {N127}
cysteine residue {C188}
MODIFICATION: cysteine residue {C202}
cysteine residue {C202}
MODIFICATION: cysteine residue {C188}
N-glycosylation site {N245}
transmembrane domain {273-294}
cytoplasmic loop {295-298}
transmembrane domain {299-320}
exoplasmic loop {321-331}
transmembrane domain {332-354}
cytoplasmic loop {355-444}
transmembrane domain {445-465}
exoplasmic domain {465-465}
Database Correlations
OMIM 137166
UniProt Q8N1C3
PFAM correlations
Entrez Gene 2565
References
- UniProt :accession Q8N1C3
- Protein Spotlight; Note: forbidden fruit -
Issue 56 of March 2005
http://www.expasy.org/spotlight/back_issues/sptlt056.shtml