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gamma-aminobutyric acid receptor subunit epsilon; GABA(A) receptor subunit epsilon (GABRE)
Function:
- GABA-A receptor subunit
Structure:
- belongs to the ligand-gated ionic channel (TC 1.A.9) family
Compartment:
- cell junction, synapse, postsynaptic cell membrane
Expression:
- expressed in many tissues
- highest levels of expression in adult heart & placenta
General
glycoprotein
ionotropic receptor subunit
transmembrane 4e protein
Properties
SIZE: entity length = 506 aa
MW = 58 kD
COMPARTMENT: plasma membrane
MOTIF: exoplasmic domain {1-253}
MOTIF: signal sequence {1-22}
N-glycosylation site {N134}
cysteine residue {C195}
MODIFICATION: cysteine residue {C209}
cysteine residue {C209}
MODIFICATION: cysteine residue {C195}
N-glycosylation site {N252}
transmembrane domain {254-274}
cytoplasmic loop {275-280}
transmembrane domain {281-301}
exoplasmic loop {302-343}
transmembrane domain {344-364}
cytoplasmic loop {365-485}
transmembrane domain {486-506}
exoplasmic domain {506-506}
Database Correlations
OMIM 300093
UniProt P78334
PFAM correlations
Entrez Gene 2564
Kegg hsa:2564
References
UniProt :accession P78334