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gamma-aminobutyric acid receptor subunit alpha-5; GABA(A) receptor subunit alpha-5 (GABRA5)
Function:
- GABA-A receptor alpha subunit
Structure:
- belongs to the ligand-gated ionic channel (TC 1.A.9) family
Compartment:
- cell junction, synapse, postsynaptic cell membrane
General
gamma-aminobutyric acid (GABA) A receptor, alpha
glycoprotein
transmembrane 4e protein
Properties
SIZE: entity length = 462 aa
MW = 52 kD
COMPARTMENT: plasma membrane
MOTIF: exoplasmic domain {1-259}
MOTIF: signal sequence {1-31}
N-glycosylation site {N45}
N-glycosylation site {N145}
cysteine residue {C173}
MODIFICATION: cysteine residue {C187}
cysteine residue {C187}
MODIFICATION: cysteine residue {C173}
N-glycosylation site {N207}
N-glycosylation site {N236}
transmembrane domain {260-281}
cytoplasmic loop {282-285}
transmembrane domain {286-307}
exoplasmic loop {308-318}
transmembrane domain {319-341}
cytoplasmic loop {342-427}
transmembrane domain {428-449}
exoplasmic domain {450-462}
Database Correlations
OMIM 137142
UniProt P31644
PFAM correlations
Entrez Gene 2558
Kegg hsa:2558
References
- UniProt :accession P31644
- Protein Spotlight; Note: forbidden fruit -
Issue 56 of March 2005
http://www.expasy.org/spotlight/back_issues/sptlt056.shtml