FXYD domain-containing ion transport regulator 5; dysadherin (FXYD5, DYSAD, IWU1, HSPC113, UNQ2561/PRO6241)

Function: - involved in down-regulation of E-cadherin, resulting in diminished cell adhesion Structure: glycoprotein Compartment: membrane Alternative splicing: named isoforms=2 Pathology: promotes metastasis

General

glycoprotein membrane protein

Properties

SIZE: MW = 19 kD entity length = 178 aa COMPARTMENT: cellular membrane MOTIF: signal sequence {1-21} glycosylation site transmembrane domain {146-164}

Database Correlations

OMIM 606669 UniProt Q96DB9 Pfam PF02038

References

UniProt :accession Q96DB9