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Fragile X mental retardation syndrome-related protein 2 (FXR2, FMR1L2)
Function:
- RNA-binding protein
- interacts with FMR1 & FXR1
- interacts with CYFIP2 but not with CYFIP1.
- interacts with TDRD3
Structure:
- belongs to the FMR1 family
- contains 2 KH domains
Compartment: cytoplasm
General
nuclear protein
phosphoprotein
RNA-binding protein
Properties
SIZE: entity length = 673 aa
MW = 74 kD
COMPARTMENT: cytoplasm
MOTIF: KH domain
SITE: 232-261
FOR-BINDING-OF: ribonucleic acid
KH domain
SITE: 295-324
FOR-BINDING-OF: ribonucleic acid
Thr phosphorylation site {T411}
serine-rich region {414-418}
MOTIF: serine residue (SEVERAL)
Ser phosphorylation site {S453}
Thr phosphorylation site {T455}
Tyr phosphorylation site {Y519}
Ser phosphorylation site {S525}
Ser phosphorylation site {S533}
arginine-rich region {544-552}
MOTIF: arginine residue (SEVERAL)
Ser phosphorylation site {S566}
arginine-rich region {584-594}
MOTIF: arginine residue (SEVERAL)
Thr phosphorylation site {T598}
Ser phosphorylation site {S601}
Ser phosphorylation site {S603}
Database Correlations
OMIM 605339
UniProt P51116
PFAM correlations
Entrez Gene 9513
Kegg hsa:9513
References
UniProt :accession P51116