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fructosamine-3-kinase (FN3K)
Function:
- may initiate a process leading to the deglycation of fructoselysine & of glycated proteins
- may play a role in phosphorylation of
a) 1-deoxy-1-morpholinofructose (DMF)
b) fructoselysine
c) fructoseglycine
d) fructose
e) glycated lysozyme monomer
Structure: belongs to the fructosamine kinase family
Expression: expressed in erythrocytes
General
kinase or ATP-phosphotransferase
Properties
SIZE: entity length = 309 aa
MW = 35 kD
MOTIF: acetylation site
SITE: N-TERMINUS
EFFECTOR-BOUND: acetyl
Ser phosphorylation site {S258}
Tyr phosphorylation site {Y263}
Database Correlations
OMIM 608425
UniProt Q9H479
Pfam PF03881
Entrez Gene 64122
Kegg hsa:64122
References
UniProt :accession Q9H479