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fractional excretion of urate
Defined as: excreted urate/filtered urate
Indications:
- evaluation of prerenal azotemia in patients on diuretics
Procedure:
Measured as:
(urine urate/serum urate) / (urine creatinine/serum creatinine)
Clinical significance:
- useful for assessing prerenal azotemia in patients with FENA > 1% & on a diuretic (FENA can be elevated by diuretics)
- fractional excretion of urate is less influenzed by diuretics than FENA
- a value of < 10% for fractional excretion of urate is consistent with prerenal azotemia
Related
fractional excretion of sodium (FENA)
urate; uric acid
General
urinary indices
References
- Medical Knowledge Self Assessment Program (MKSAP) 16
American College of Physicians, Philadelphia 2012