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forkhead box protein S1; forkhead-like 18 protein; forkhead-related transcription factor 10; FREAC-10 (FOXS1 FKHL18 FREAC10)
Function:
- transcriptional repressor
- suppresses transcription from the FASLG, FOXO3 & FOXO4 promoters
- may have a role in organization of the testicular vasculature
Structure:
- contains 1 fork-head DNA-binding domain
Compartment: nucleus (putative)
General
forkhead family transcription factor
transcriptional silencer (transcriptional repressor)
Properties
SIZE: entity length = 330 aa
MW = 35 kD
COMPARTMENT: cell nucleus
MOTIF: fork head domain
NAME: fork head domain
SITE: 17-108
Database Correlations
OMIM 602939
UniProt O43638
Pfam PF00250
Entrez Gene 2307
Kegg hsa:2307
References
- Entrez Gene :accession 2307
- UniProt :accession O43638