forkhead box protein O6 (FOXO6)

Function: - transcriptional activator (putative) - phosphorylation of Ser-184 is be important in regulating the transacriptional activity (putative) Structure: contains 1 fork-head DNA-binding domain Compartment: - cytoplasm, nucleus - when phosphorylated, translocated from nucleus to cytoplasm - high nuclear localization after stimulation with growth factors (putative)

General

forkhead family transcription factor phosphoprotein

Properties

SIZE: entity length = 492 aa MW = 51 kD COMPARTMENT: cytoplasm cell nucleus MOTIF: fork head domain NAME: fork head domain SITE: 88-182 Ser phosphorylation site {S184} glycine-rich region {305-408} alanine-rich region {349-429} MOTIF: alanine residue (SEVERAL) proline-rich region SITE: 473-485 MOTIF: proline residue (SEVERAL)

Database Correlations

UniProt A8MYZ6 Entrez Gene 343552

References

UniProt :accession A8MYZ6