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forkhead box protein G1; forkhead box protein G1A; forkhead box protein G1B; forkhead box protein G1C; transcription factor BF-1; transcription factor BF-2; brain factor 2; drosophila forkhead homolog-like 2 (FKHL2, FOXG1A, FOXG1B, FOXG1C, FOXG1, FKHL1, FKHL2, FKHL3, FKHL4)
Function:
- transcription repression facto
- role in establishment of regional subdivision of developing brain & in development of the telencephalon
- interacts with JARID1B
Structure: contains 1 fork-head DNA-binding domain
Compartment: nucleus
Expression: restricted to neurons of developing telencephalon
General
forkhead family transcription factor
Properties
SIZE: MW = 52 kD
entity length = 489 aa
COMPARTMENT: cell nucleus
MOTIF: histidine-rich region {33-57}
MOTIF: histidine residue (SEVERAL)
proline-rich region
SITE: 58-112
MOTIF: proline residue (SEVERAL)
glycine-rich region {118-177}
fork head domain
NAME: fork head domain
SITE: 181-275
JARID1B interaction {383-406}
Database Correlations
OMIM correlations
UniProt P55316
LOCUS-LINK correlations
References
- Entrez Gene :accession 2291
- UniProt :accession P55316