Search
forkhead box protein A2; hepatocyte nuclear factor 3-beta; HNF-3B (FOXA2)
Function:
- transcription activator for a number of liver genes including AFP, albumin, tyrosine aminotransferase, PEPCK
- interacts with cis-acting regulatory regions of these genes
- binds TLE1
Structure: contains 1 fork-head DNA-binding domain
Compartment: nucleus
General
forkhead family transcription factor
Properties
SIZE: MW = 48 kD
entity length = 457 aa
COMPARTMENT: cell nucleus
MOTIF: fork head domain
NAME: fork head domain
SITE: 159-252
Database Correlations
OMIM 600288
UniProt Q9Y261
Pfam PF00250
Entrez Gene 3170
References
- Entrez Gene :accession 3170
- UniProt :accession Q9Y261