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Folgard Rx 2.2 (folate, B12, B6)

vitamin amount other amount Folate 2.2 mg 2.5 mg Vitamin B12 500 ug 400 ug Vitamin B6 15 mg 25 mg Indications: 1) treatment of folate, vitamin B12 or vitamin B6 deficiency 2) treatment of hyperhomocysteinemia 3) NO benefit for secondary stroke prevention [1] Dosage: 1 tab PO QD Mechanism of action: - diminished mean serum homocysteine levels from 13.4 umo/L to 11 umol/L

General

metabolic agent (metabolic modifier) pharmacologic combination

References

  1. Journal Watch 24(5):8, 2004 - Toole JF et al Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA 291:565, 2004 PMID: 14762035

Components

cyanocobalamin (vitamin B12, Betalin-12, Redisol, Rubramin-PC) folic acid; folate; vitamin B9 pyridoxine (a vitamin B6)