fms receptor

macrophage colony stimulating factor receptor

Specific

gp140 v-fms oncoprotein macrophage colony-stimulating factor 1 receptor; CSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; proto-oncogene c-Fms; CD115 (CSF1R, FMS)

General

colony-stimulating factor [CSF] receptor tyrosine kinase receptor (RTK)

Properties

COMPARTMENT: plasma membrane CELL: macrophage STATE: active state MOTIF: ligand-binding site transmembrane domain cysteine residue box1 motif FOR-BINDING-OF: Janus kinase (JAK) box2 motif FOR-BINDING-OF: Janus kinase (JAK) Tyr phosphorylation site kinase domain MOTIF: ATP-binding site NAME: ATP-binding site