FMRFamide-related peptides; contains: neuropeptide SF; NPSF; contains: neuropeptide FF; NPFF; contains: neuropeptide AF; NPAF (NPFF)

Function: - morphine modulating peptides - FMRFamide-related peptides have wide-ranging physiologic effects, including a) modulation of morphine-induced analgesia b) elevation of arterial blood pressure c) increased somatostatin secretion from the pancreas - neuropeptide FF potentiates & sensitizes ACCN2 & ACCN3 channels Structure: - belongs to the FARP (FMRFamide related peptide) family Compartment: secreted

General

peptide precursor secreted protein

Properties

SIZE: entity length = 113 aa MW = 12 kD COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-20}

Database Correlations

OMIM 604643 UniProt O15130 Entrez Gene 8620 Kegg hsa:8620

References

UniProt :accession O15130