fetal liver kinase-2 (flk-2)

Expression: - expressed in hematopoietic populations enriched for stem cells & primitive uncommitted progenitors - absent in populations containing more mature cells

Properties

SIZE: entity length = 990 aa COMPARTMENT: plasma membrane STATE: active state MOTIF: ligand-binding site transmembrane domain Tyr phosphorylation site kinase domain MOTIF: ATP-binding site NAME: ATP-binding site

References

Matthews et al. Cell 65:1143-52 1991