FK506 binding protein (FKBP)

Function: - FK506- & rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways - PPIases accelerate the folding of proteins

Specific

FK506-binding protein 10 (65 kD FK506-binding protein, immunophilin FKBP65, FKBP10) FK506-binding protein 11 (19 kD FK506-binding protein, FKBP11, FKBP19) FK506-binding protein 14 (22 kD FK506-binding protein, FKBP14, FKBP22) FK506-binding protein 1A (12 kD FK506-binding protein, immunophilin FKBP12, FKBP1A) FK506-binding protein 1B (12.6 kD FK506-binding protein, immunophilin FKBP12.6, FKBP1B) FK506-binding protein 2 (13 kD FK506-binding protein, FKBP2) FK506-binding protein 3, 25 kD FK506-binding protein or rapamycin-selective 25 kD immunophilin FK506-binding protein 4 (52 kD FK506 binding protein, hsp-binding immunophilin, FKBP59, FKBP4) FK506-binding protein 5 (51 kD FK506-binding protein, 54 kD progesterone receptor-associated immunophilin, FKBP54, FF1 antigen, HSP90-binding immunophilin, androgen-regulated protein 6, FKBP5) FK506-binding protein 6 (36 kD FK506-binding protein, immunophilin FKBP36, FKBP6) FK506-binding protein 7 FK506-binding protein 8 (38 kD FK506-binding protein homolog, FKBP8, FKBP38, FKBPR38) FK506-binding protein 9 (FKBP9 FKBP60 FKBP63) FK506-binding protein 9-like protein (FKBP9L)

Properties

MOTIF: active site