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fibrinogen-like protein 1; HP-041; hepassocin; hepatocyte-derived fibrinogen-related protein 1; HFREP-1; liver fibrinogen-related protein 1; LFIRE-1 (FGL1 HFREP1)
Function:
- hepatocyte mitogenic activity
Structure: homodimer (putative)
Compartment: secreted
Expression: liver specific
Related
fibroleukin; fibrinogen-like protein 2; pT49 (FGL2)
General
glycoprotein
Properties
SIZE: entity length = 312 aa
MW = 36 kD
MOTIF: signal sequence {1-22}
coiled coil {23-61}
MOTIF: cysteine residue {C26}
MODIFICATION: cysteine residue {C-INTERCHAIN}
Fibrinogen C-terminal {74-306}
MOTIF: cysteine residue {C83}
MODIFICATION: cysteine residue {C112}
cysteine residue {C112}
MODIFICATION: cysteine residue {C83}
cysteine residue {C248}
MODIFICATION: cysteine residue {C261}
cysteine residue {C261}
MODIFICATION: cysteine residue {C248}
Database Correlations
OMIM 605776
UniProt Q08830
Pfam PF00147
Entrez Gene 2267
Kegg hsa:2267
References
- UniProt :accession Q08830
- SeattleSNPs
http://pga.gs.washington.edu/data/fgl1/