Search
ferric-chelate reductase 1 (stromal cell-derived receptor 2, SDR-2, FRRS1, SDFR2, SDR2)
Function:
- ferric-chelate reductases reduce Fe+3 to Fe+2 before its transport from the endosome to the cytoplasm (putative)
Cofactor: binds 2 heme groups non-covalently (putative)
Structure:
- belongs to the FRRS1 family
- contains 1 cytochrome b561 domain
- contains 1 DOMON domain
- contains 1 reelin domain
Compartment: membrane (putative)
Alternative splicing: named isoforms=2
General
glycoprotein
membrane protein
oxidoreductase
Properties
SIZE: entity length = 592 aa
MW = 66 kD
COMPARTMENT: cellular membrane
MOTIF: transmembrane domain {2-22}
Reelin {13-179}
MOTIF: N-glycosylation site {N138}
DOMON {216-331}
MOTIF: N-glycosylation site {N308}
Cytochrome b561 {335-534}
MOTIF: transmembrane domain {372-392}
Iron [Fe]-binding site
SITE: 373-373
Iron [Fe]-binding site
SITE: 414-414
transmembrane domain {415-435}
Iron [Fe]-binding site
SITE: 442-442
transmembrane domain {446-466}
Iron [Fe]-binding site
SITE: 471-471
transmembrane domain {491-511}
transmembrane domain {515-535}
transmembrane domain {569-589}
Database Correlations
UniProt Q6ZNA5
PFAM correlations
Kegg hsa:3910
References
UniProt :accession Q6ZNA5