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far upstream element-binding protein 3; FUSE-binding protein 3 (FUBP3, FBP3)

Function: - may interact with single-stranded DNA from the far-upstream element (FUSE) - may activate gene expression - phosphorylated upon DNA damage, probably by ATM or ATR Structure: contains 4 KH domains Compartment: nucleus (probable) Alternative splicing: named isoforms=2 Expression: detected in a number of cell lines

General

Far upstream element binding protein (FUSE binding protein) phosphoprotein

Properties

SIZE: entity length = 572 aa MW = 62 kD COMPARTMENT: cell nucleus MOTIF: acetylation site SITE: N-TERMINUS EFFECTOR-BOUND: acetyl KH domain SITE: 77-141 FOR-BINDING-OF: ribonucleic acid KH domain SITE: 162-228 FOR-BINDING-OF: ribonucleic acid KH domain SITE: 253-317 FOR-BINDING-OF: ribonucleic acid MOTIF: Ser phosphorylation site {S296} KH domain SITE: 354-421 FOR-BINDING-OF: ribonucleic acid Ser phosphorylation site {S569}

Database Correlations

OMIM 603536 UniProt Q96I24 Pfam PF00013 Entrez Gene 8939 Kegg hsa:8939

References

UniProt :accession Q96I24