eyk proto-oncogene receptor tyrosine kinase (chicken)

The eyk proto-oncogene receptor tyrosine kinase was originally identified as the product of a chicken retroviral transforming gene.

General

aves-specific molecule proto oncogene protein tyrosine kinase receptor (RTK)

Properties

COMPARTMENT: plasma membrane STATE: active state MOTIF: ligand-binding site transmembrane domain Tyr phosphorylation site kinase domain MOTIF: ATP-binding site NAME: ATP-binding site

References

- Varnum BC et al Axl receptor tyrosine kinase stimulated by the vitamin K- dependent protein encoded by growth-arrest-specific gene 6. Nature 373:623 1995 PMID: 7854420