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exosome component 1; 3'-5' exoribonuclease CSL4 homolog; CGI-108 (EXOSC1, CSL4)

Function: - component of the exosome 3'->5' exoribonuclease complex - also associated with the GTPase Ran Structure: - N- & C-terminal regions of the protein are required for interaction with RRP46 - contains 1 S1 motif domain Compartment: nucleus, nucleolus

General

nuclear protein protein subunit

Properties

SIZE: MW = 21 kD entity length = 195 aa COMPARTMENT: cell nucleus

Database Correlations

OMIM 606493 UniProt Q9Y3B2 Kegg hsa:5101

References

UniProt :accession Q9Y3B2

Component-of

exosome multienzyme ribonuclease complex