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exosome component 1; 3'-5' exoribonuclease CSL4 homolog; CGI-108 (EXOSC1, CSL4)
Function:
- component of the exosome 3'->5' exoribonuclease complex
- also associated with the GTPase Ran
Structure:
- N- & C-terminal regions of the protein are required for interaction with RRP46
- contains 1 S1 motif domain
Compartment: nucleus, nucleolus
General
nuclear protein
protein subunit
Properties
SIZE: MW = 21 kD
entity length = 195 aa
COMPARTMENT: cell nucleus
Database Correlations
OMIM 606493
UniProt Q9Y3B2
Kegg hsa:5101
References
UniProt :accession Q9Y3B2
Component-of
exosome multienzyme ribonuclease complex