exosome complex exonuclease RRP44 (ribosomal RNA processing protein 44, DIS3 protein homolog, DIS3, KIAA1008, RRP44)

Function: - component of the exosome 3'->5' exoribonuclease complex - also associated with the GTPase Ran Structure: - belongs to the ribonuclease II (RNB) family - contains 1 PINc domain Compartment: cytoplasm, nucleus, nucleolus Alternative splicing: named isoforms=2 Expression: widely expressed

General

nuclear protein protein subunit

Properties

SIZE: entity length = 958 aa MW = 109 kD COMPARTMENT: cytoplasm cell nucleus MOTIF: PINc {64-182}

Database Correlations

OMIM 607533 UniProt Q9Y2L1 Pfam PF00773 Kegg hsa:2289

References

UniProt :accession Q9Y2L1