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evolutionary divergent human protein

Genetics: - proteins derived from genes that have diverged from those of other primates since the origins of Homo sapiens. - these proteins, relatively few in number, perhaps a hundred or so, may play a role in the differential longevity & intelligence of humans compared with other primates.

Related

evolutionary divergent human gene human longevity protein

Specific

aquaporin-7; AQP-7; aquaporin adipose; AQPap (AQP7, AQP7L, AQP9) baculoviral IAP repeat-containing protein 1; neuronal apoptosis inhibitory protein (NAIP, BIRC1) cytidine monophosphate-N-acetylneuraminic acid hydroxylase-like; CMP-NeuAc hydroxylase-like protein (CMAH, CMAHP) DBH-like monooxygenase protein 2 (MOXD2P, MOXD2) exonuclease GOR; antigen GOR homolog; RNA exonuclease 1 homolog-like 1 (REXO1L1, GOR) G protein-coupled receptor 127; EGF-like module containing mucin-like hormone receptor-like 4 (GPR127, EMR4, EMR4P) kallikrein-8; hK8; neuropsin; NP; ovasin; serine protease 19; serine protease TADG-14; tumor-associated differentially expressed gene 14 protein (KLK8 NRPN PRSS19 TADG14 UNQ283/PRO322) miR-941 Na+/Cl- dependent GABA transporter 2; solute carrier family 6 member 13 (SLC6A13) nicotinic receptor alpha-7, neuronal acetylcholine receptor subunit alpha-7 (CHRNA7, NACHRA7, alpha 7 nAChR) notch homolog 2 N-terminal-like protein B (NOTCH2NLB) notch homolog 2 N-terminal-like protein C (NOTCH2NLC) p21-activated kinase 2 (PAK2), S6/H4 kinase, PAK65 or gamma-PAK protein ADORA2A-AS1; ADORA2A antisense RNA 1; ADORA2A antisense gene protein 1 (ADORA2A-AS1, C22orf45) protein C20orf203 (C20orf203) protein DNAH10OS (DNAH10OS) Rho guanine nucleotide exchange factor 5; ephexin-3; guanine nucleotide regulatory protein TIM; oncogene TIM; transforming immortalized mammary oncoprotein; p60 TIM (ARHGEF5, TIM) rho-associated coiled-coil-containing protein kinase 1; p160ROCK; ROK-beta; Rho-associated protein kinase 1 (ROCK1) SLIT-ROBO Rho GTPase-activating protein 2; srGAP2; formin-binding protein 2; Rho GTPase-activating protein 34 (SRGAP2, ARHGAP34, FNBP2, KIAA0456, SRGAP2A) SLIT-ROBO Rho GTPase-activating protein 2B; SLIT-ROBO Rho GTPase activating protein 2 pseudogene 2 (SRGAP2B, SRGAP2P2) SLIT-ROBO Rho GTPase-activating protein 2C; SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1 (SRGAP2C, SRGAP2P1) SLIT-ROBO Rho GTPase-activating protein 3; srGAP3; mental disorder-associated GAP; Rho GTPase-activating protein 14; WAVE-associated Rac GTPase-activating protein; WRP; srGAP2 (SRGAP3, ARHGAP14, KIAA0411, KIAA1156, MEGAP, SRGAP2) transmembrane protein 183B (TMEM183B, C1orf37-dup) ubiquitin carboxyl-terminal hydrolase 10; deubiquitinating enzyme 10; ubiquitin thiolesterase 10; ubiquitin-specific-processing protease 10 (USP10, KIAA0190) ubiquitin carboxyl-terminal hydrolase 14; deubiquitinating enzyme 14; ubiquitin thiolesterase 14; ubiquitin-specific-processing protease 14 (USP14, TGT) vomeronasal type-1 receptor 1 (V1r-like receptor 1, vomeronasal olfactory receptor chromosome 19 subtype I member 1, V3r-related gene protein, hGPCR24, VN1R1, V1RL1, VNR19I1, ZVNH1) vomeronasal type-1 receptor 2; V1r-like receptor 2; hGPCR25 (VN1R2, V1RL2) vomeronasal type-1 receptor 3; V1r-like receptor 3 (VN1R3, V1RL3, FKSG46) vomeronasal type-1 receptor 4 (V1r-like receptor 4, hGPCR27, VN1R4, V1RL4) vomeronasal type-1 receptor 5; V1r-like receptor 5; hGPCR26 (VN1R5, V1RL5) WAS protein family homolog; protein FAM39DP (WASH)

General

evolutionary divergent primate protein

References

  1. Fortna A, Kim Y, MacLaren E, Marshall K, Hahn G, Meltesen L, Brenton M, Hink R, Burgers S, Hernandez-Boussard T, Karimpour- Fard A, Glueck D, McGavran L, Berry R, Pollack J, Sikela JM. Lineage-specific gene duplication and loss in human and great ape evolution. PLoS Biol. 2004 Jul;2(7):E207. Epub 2004 Jul 13. PMID: 15252450