eunuchism

Testicular failure. Etiology: 1) congenital 2) acquired Clinical manifestations: 1) prepubertal a) hypoplastic penis & testis b) thin smooth skin c) failure of the voice to deepen d) female eschutcheon of pubic hair e) absence of beard f) poor muscular development g) long limbs h) broad hips i) gynecomastia 2) postpubertal a) testicular atrophy b) pallor Laboratory: - urine chemistries: 1) normal or low androgens & 17-ketosteroids 2) high urinary gonadotropins Radiology: delayed closure of epiphyses.

References

DeGowin & DeGowin's Diagnostic Examination, 6th edition, RL DeGowin (ed), McGraw Hill, NY 1994, pg 884