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ethyl glucuronide in urine
Indications:
- alcoholism in remission
Reference interval:
- three different test levels are commonly available:
a) 100 ng/mL testing
1] most commonly used to monitor individuals for professional or clinical reasons, such as impaired health professionals
2] often used by criminal justice agencies
3] testing at this level will occasionally pick up incidental exposure
b) 250 ng/mL testing
1] detects about 97% of episodes of alcohol use compared with 100 ng/mL testing
2] high enough cut-off to avoid most incidental exposure
c) 500 ng/mL testing
1] detects about 90% of episodes of alcohol use compared with 100 ng/mL testing
2] used increasingly, especially for routine clinical & forensic applications
3] most inadvertent alcohol exposures result in levels below 500 ng/mL
Clinical significance:
- an elimination product of ingested ethanol
- appears in urine for up to 80-hours after consumption
- more sensitive & reliable indicator of both drinking & abstinence than urine alcohol
- detects alcohol consumption up to 3.5 days from the time of urine collection
- detectable in urine up to 5 days after heavy binge drinking [2]
Procedure:
- testing is a process similar to other lab-based drugs of abuse testing
- a chain of custody process is followed
Methods:
- LC/MS/MS; liquid chromatography with mass spectroscopy
Related
ethyl glucuronide
Specific
ethyl glucuronide in urine confirmatory
ethyl glucuronide in urine screen
General
ethyl glucuronide in specimen
urine toxicology
References
- Ethylglucuronide (EtG)
http://www.ethylglucuronide.net/
- Soreff S
Fast Five Quiz: Alcohol Use and Abuse.
Medscape. Jan 3, 2019
https://reference.medscape.com/viewarticle/906757_6
Component-of
ethyl glucuronide/creatinine in urine