ethanolamine kinase 2; EKI 2; ethanolamine kinase-like protein (ETNK2, EKI2, HMFT1716)

Function: - highly specific for ethanolamine phosphorylation - does not have choline kinase activity (putative) - phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3 ATP + ethanolamine = ADP + O-phosphoethanolamine Structure: belongs to the choline/ethanolamine kinase family Alternative splicing: named isoforms=3 Expression: - expressed in kidney, liver, ovary, testis & prostate

Properties

SIZE: entity length = 386 aa MW = 45 kD MOTIF: kinase domain MOTIF: ATP-binding site NAME: ATP-binding site

Database Correlations

OMIM 609859 UniProt Q9NVF9 Pfam PF01633 Entrez Gene 55224 Kegg hsa:55224 ENZYME 2.7.1.82

References

UniProt :accession Q9NVF9