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erythroid transcription factor-1 (ETF1)
Function:
- binding sites for ETF1 are widely distributed in the promoters & enhancers of the globin gene family & other erythroid-specific genes
Pathology:
- aberrant binding of ETF1 to a mutant site has been implicated in one type of hereditary persistence of fetal hemoglobin
General
transcription factor (TF)
Properties
COMPARTMENT: cell nucleus
CELL: ERYTHOID-PRECURSOR
MOTIF: Zinc finger
NAME: Zinc finger (2)
EFFECTOR-BOUND: Zn+2
Database Correlations
OMIM 305371
MORBIDMAP 305371
References
OMIM :accession 305371