erythroid membrane-associated protein; hERMAP; Scianna blood group antigen; Radin blood group antigen (ERMAP, RD)

Function: - cell-adhesion or receptor molecule of erythroid cells (putative) Structure: glycosylated Compartment: cell membrane Expression: - expressed in bone marrow > leukocytes, thymus, lymph node, spleen - expressed in fetal liver blood cells Polymorphism: - ERMAP is responsible for the Scianna/Radin blood group system

General

glycoprotein membrane protein

Properties

SIZE: MW = 53 kD entity length = 475 aa COMPARTMENT: cytoplasm MOTIF: signal sequence {1-29} immunoglobulin superfamily domain {30-140} MOTIF: cysteine residue {C50} MODIFICATION: cysteine residue {C126} cysteine residue {C126} MODIFICATION: cysteine residue {C50} N-glycosylation site {N132} transmembrane domain {156-176} B30.2/SPRY {220-418}

Database Correlations

OMIM correlations UniProt Q96PL5 PFAM correlations

References

UniProt :accession Q96PL5