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erythroid differentiation related factor; erythroid associated factor; ERAF; alpha-hemoglobin-stabilizing protein; AHSP (EDRF)

Function: 1) chaperone to prevent aggregation of alpha-globin during erythroid cell maturation 2) protects free alpha-globin from precipitation Pathology: - modulates pathological states of alpha-globin excess, i.e. beta-thalassemia

General

transcription factor (TF)

Properties

SIZE: MW = 12 kD entity length = 102 aa COMPARTMENT: cell nucleus

Database Correlations

OMIM 605821 UniProt Q9NZD4

References

  1. OMIM :accession 605821
  2. UniProt :accession Q9NZD4