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spherocyte

Spherocytes are small hyperchromic erythrocytes on peripheral smears, lacking central pallor. Mean corpuscular volume is not reduced. Etiology: 1) hereditary spherocytosis 2) extravascular hemolysis a) autoimmune warm hemolytic anemia b) glucose-6-phosphate dehydrogenase deficiency 3) splenectomy 4) Clostridium infections 5) hypophosphatemia

Related

spherocytes in body fluid spherocytosis (microspherocytosis)

General

erythrocyte; red blood cell (RBC)

Properties

QUANTITY: 4.2E12-6.2E12 CELLS/UL

References

  1. Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 414
  2. Medical Knowledge Self Assessment Program (MKSAP) 17, 18. American College of Physicians, Philadelphia 2015, 2018.