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erythrocyte urea transporter (Kidd blood group, solute carrier family 14 member 1, SLC14A1, HUT11, JK, RACH1, UT1, UTE)

Function: - low-affinity urea transporter - mediates urea transport in erythrocytes Compartment: membrane Expression: erythrocytes Polymorphism: - SLC14A1 is responsible for the Kidd blood group system)

Related

Kidd blood group locus SLC14A1 gene mutation

General

glycoprotein membrane protein solute carrier family 14 (SLC14, SLC14A)

Properties

SIZE: MW = 43 kD entity length = 389 aa COMPARTMENT: cellular membrane MOTIF: transmembrane domain {53-73} transmembrane domain {78-98} transmembrane domain {116-136} transmembrane domain {143-163} transmembrane domain {173-193} N-glycosylation site {N211} transmembrane domain {243-263} transmembrane domain {281-301} transmembrane domain {310-330} transmembrane domain {333-353}

Database Correlations

OMIM 111000 UniProt Q13336 Pfam PF03253

References

  1. UniProt :accession Q13336
  2. BGMUT; Blood group antigen gene mutation database http://www.ncbi.nlm.nih.gov/projects/mhc/xslcgi.fcgi?cmd=bgmut/systems_info&system=kidd
  3. GeneReviews https://www.genecards.org/cgi-bin/carddisp.pl?gene=SLC14A1
  4. SeattleSNPs http://pga.gs.washington.edu/data/slc14a1/