ermin (juxtanodin, JN, ERMN, KIAA1189)

Function: - role in cytoskeletal rearrangements during the late wrapping &/or compaction phases of myelinogenesis - role in maintenance & stability of myelin sheath in the adult - role in late-stage oligodendroglia maturation, myelin & Ranvier node formation during CNS development - role in maintenance & plasticity of related structures in the mature CNS - binds actin (putative) Compartment: cytoplasm, cytoskeleton (putative) Expression: - highly expressed in adult & fetal brain - expressed at intermediate levels in the lung & liver

Properties

SIZE: entity length = 284 aa MW = 33 kD COMPARTMENT: cytoplasm MOTIF: Binds actin {265-284}

Database Correlations

UniProt Q8TAM6 Pfam PF00769 Kegg hsa:5747

References

UniProt :accession Q8TAM6