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epithelial basement membrane corneal dystrophy; Cogan corneal dystrophy; map-dot-fingerprint type corneal dystrophy
Pathology:
- bilateral anterior corneal dystrophy
- abnormal, redundant basement membrane
- intraepithelial lacunae filled with cellular debris
Genetics:
- usually is not considered to be inherited; however, families with autosomal dominant inheritance have been identified
- associated with defects in TGFBI
Special laboratory:
- slit-lamp examination
- grayish epithelial fingerprint lines
- geographic map-like lines, & dots (or microcysts)
General
corneal disease (keratopathy)
genetic disease of the eye
Database Correlations
OMIM 121820
References
OMIM :accession 121820