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epinephrine/pilocarpine (E-Pilo-x PxEx)

Indications: 1) treatment of glaucoma 2) counter effects of cycloplegics Dosage: 1-2 drops up to 6 times/day Ophthalmic solution: epinephrine bitartrate 1% & pilocarpine HCl - 1%: E-pilo-1, P1E1 (15 mL) - 2%: E-pilo-2, P2E1 (15 mL) - 3%: E-pilo-3, P3E1 (15 mL) - 4%: E-pilo-4, P4E1 (15 mL) - 5%: E-pilo-5, P5E1 (15 mL) - 6%: E-pilo-6, P6E1 (15 mL) Adverse effects: - not common (1-10%) - miosis, ciliary spasm, blurred vision, retinal detachment, stinging, lacrimation, itching, vitreous hemorrhage, headache, photophobia, acute iritis, hypersensitivity, tachycardia, salivation, hypertension

General

pharmacologic combination

References

Kaiser Permanente Northern California Regional Drug Formulary, 1998

Components

epinephrine; adrenaline (Sus-Phrine, Vapronefrin, Epifrin, Glaucon, Auvi-Q, Allerject) pilocarpine (Pilocar, Isopto Carpine, Salagen, Ocusert Pilo)