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epidural electrical stimulation
Indications:
- epidural electrical stimulation L1 to S1-S2 in combination with physical therapy may enable paraplegic patients to walk again (with assistance) [1]
- epidural electrical stimulation targeting the ensemble of dorsal roots involved in leg & trunk movements enabled 3 individuals with complete lower extremity sensorimotor paralysis to stand, walk, cycle, swim & control trunk movements within one day [2]
General
electrical stimulation
References
- Gill ML, Grahn PJ, Calvert JS et al
Neuromodulation of lumbosacral spinal networks enables
independent stepping after complete paraplegia.
Nature Medicine (2018). Sept 24
PMID: 30250140
https://www.nature.com/articles/s41591-018-0175-7
- Anderson P
Motor Function Restored in Three Men After Complete Paralysis From Spinal Cord Injury.
Medscape. Feb 7, 2022
https://www.medscape.com/viewarticle/967969
- George J
Stimulation Helps Paralyzed People Stand, Walk Within Hours of Surgery.
Targeting dorsal roots restored motor function quickly, first-in-man study shows.
MedPage Today February 7, 2022
https://www.medpagetoday.com/neurology/generalneurology/97061
- Rowald A, Komi S, Demesmaeker R et al
Activity-dependent spinal cord neuromodulation rapidly restores trunk and
leg motor functions after complete paralysis.
Nat Med 2022. Feb 7
PMID: 35132264