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epidermodysplasia verruciformis

Etiology: 1) all warts are caused by human papilloma virus (HPV) 2) HPV types 3,5,8,9,10,12,14,15,17,19-25, 28,29 Epidemiology: rare Pathology: - abnormal susceptibility to infection by specific HPV types Genetics: 1) autosomal recessive 2) associated with defects in TMC6 gene associated with defects in TMC8 gene Clinical manifestations: - numerous HPV papules & macules Complications: - malignant transformation is common.

Related

papillomavirus

General

verruca vulgaris (warts) genetic disease of the skin (genodermatosis)

Database Correlations

OMIM 226400

References

  1. Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 958
  2. Anderson, Advance/Laboratory June 2001, pg 91