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epidermal growth factor (EGF) receptor kinase substrate 8-like protein 3; EPS8-like protein 3; epidermal growth factor receptor pathway substrate 8-related protein 3; EPS8-related protein 3 (EPS8L3 EPS8R3)
Function:
- interacts with ABI1
- component of complex containing SOS1, ABI1, EPS8L2
- interacts with FASLG
Structure:
- belongs to the EPS8 family
- contains 1 SH3 domain
Compartment: cytoplasm
Alternative splicing: named isoforms=3
General
epidermal growth factor receptor kinase substrate 8-like protein (EPS8-like protein, EPS8L)
Properties
SIZE: entity length = 593 aa
MW = 67 kD
COMPARTMENT: cytoplasm
MOTIF: proline-rich region
SITE: 170-235
MOTIF: proline residue (SEVERAL)
src homology 3 [SH3] domain
SITE: 450-509
Database Correlations
UniProt Q8TE67
PFAM correlations
Entrez Gene 79574
Kegg hsa:79574
References
UniProt :accession Q8TE67