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EP300-interacting inhibitor of differentiation 3 (EID-3, EID-1-like inhibitor of differentiation 3, E1A-like inhibitor of differentiation 3, EID3)
Function:
- repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation
- may function as a coinhibitor of other CREBBP/EP300- dependent transcription factors
- interacts with the C-terminal region of CREBBP
Structure: belongs to the NSE4 family
Compartment:
- nucleus, cytoplasm
- may shuttle between nucleus & cytoplasm
Expression: highly expressed in testis
General
EP300-interacting inhibitor of differentiation (EID, E1A-like inhibitor of differentiation, CREBBP/EP300 inhibitory protein)
Properties
SIZE: entity length = 333 aa
MW = 38 kD
COMPARTMENT: cytoplasm
cell nucleus
Database Correlations
UniProt Q8N140
Pfam PF08743
Kegg hsa:4938
References
UniProt :accession Q8N140