endothelial cell-selective adhesion molecule (ESAM)

Function: 1) mediates aggregation via homophilic molecular interaction 2) interacts with BAIAP1 Structure: - contains 1 Ig-like C2-type domain - contains 1 Ig-like V-type domain Compartment: cell junction, adherens junction, tight junction Expression: expressed in endothelial cells

General

adhesion receptor glycoprotein

Properties

SIZE: MW = 41 kD entity length = 390 aa COMPARTMENT: cellular membrane MOTIF: signal sequence {1-29} immunoglobulin superfamily domain {30-143} MOTIF: N-glycosylation site {N108} immunoglobulin superfamily domain {153-242} MOTIF: N-glycosylation site {N169} cysteine residue {C174} MODIFICATION: cysteine residue {C224} N-glycosylation site {N213} cysteine residue {C224} MODIFICATION: cysteine residue {C174} N-glycosylation site {N236} transmembrane domain {249-269}

Database Correlations

UniProt Q96AP7 PFAM correlations

References

UniProt :accession Q96AP7