endogenous retroviral Pol protein selections

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endogenous retroviral Pol protein

See viral POL protein Function: - endogenous retroviral proteins may have kept, lost or modified their original function during evolution Structure: - contains 1 integrase catalytic domain - contains 1 integrase-type DNA-binding domain - contains 1 integrase-type zinc finger - contains 1 reverse transcriptase domain - contains 1 RNase H domain Expression: - synthesized as Gag-Pro & Gag-Pro-Pol polyprotein precursors

endogenous retroviral GAG polyprotein viral POL protein

Specific

HERV-K 11q22.1 provirus ancestral Pol protein [Includes: reverse transcriptase (RT); ribonuclease H (RNase H); integrase (IN)] HERV-K 19p13.11 provirus ancestral Pol protein (HERV-K113 Pol protein, [Includes: Reverse transcriptase (RT); Ribonuclease H (RNase H); Integrase (IN)]) HERV-K 19q12 provirus ancestral Pol protein (HERV-K(C19) Pol protein, [Includes: Reverse transcriptase (RT); Ribonuclease H (RNase H); Integrase (IN)]) HERV-K 1q22 provirus ancestral Pol protein (HERV-K102 Pol protein, HERV-K(III) Pol protein, [Includes: Reverse transcriptase (RT); Ribonuclease H (RNase H); Integrase (IN)]) HERV-K 1q23.3 provirus ancestral Pol protein; HERV-K18 Pol protein; HERV-K110 Pol protein; HERV-K(C1a) Pol protein [Includes: reverse transcriptase; ribonuclease H (RNase H)] HERV-K 3q27.3 provirus ancestral Pol protein ([Includes: Reverse transcriptase (RT); Ribonuclease H (RNase H); Integrase (IN)]) HERV-K 5q33.3 provirus ancestral pol protein; HERV-K10 pol protein; HERV-K107 pol protein (includes: reverse transcriptase; RT, ribonuclease H; Rnase H, integrase; IN) HERV-K 7p22.1 provirus ancestral Pol protein (HERV-K(HML-2.HOM) Pol protein, HERV-K108 Pol protein, HERV-K(C7) Pol protein, [Includes: Reverse transcriptase (RT); Ribonuclease H (RNase H); Integrase (IN)], ERVK6) HERV-K 8p23.1 provirus ancestral Pol protein (HERV-K115 Pol protein, [Includes: Reverse transcriptase (RT); Ribonuclease H (RNase H); Integrase (IN)])

General

DNA-binding protein endogenous retroviral protein reverse transcriptase (SuperScript)

Properties

COMPARTMENT: cell nucleus MOTIF: DNA-binding motif active site

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