elongin A3; RNA polymerase 2 transcription factor SIII subunit A3 (EloA3, TCEB3C, TCEB3L2)

Function: - component of elongin - subunit A3 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the elongin BC complex Structure: - elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x(3)-C-x(3)-[AILV] - contains 1 TFIIS N-terminal domain Compartment: nucleus Expression: widely expressed

Properties

SIZE: entity length = 546 aa MW = 60 kD COMPARTMENT: cell nucleus MOTIF: TFIIS N-terminal {5-80} Activation domain {308-467} MOTIF: elongin BC interaction {336-345}

Database Correlations

PFAM correlations Entrez Gene 162699

References

UniProt :accession Q8NG57 deprecated)